IgA nephropathy is a chronic disease that is immune-mediated primary glomerular disease. IgA nephropathy is often not evident in the early stages of kidney disease and is easily overlooked by patients, thus delaying the best time for the treatment of kidney disease. When patients with IgA nephropathy have obvious symptoms of kidney disease, they will go to a kidney hospital for treatment. After a related renal examination, they will know that they are IgA nephropathy. The common clinical manifestations of IgA nephropathy are as follows:
Some patients with IgA nephropathy will appear edema in the clinic. In addition, accompanied by edema in the body, may also be associated with reduced urine output, urinary frequency (especially at night) and other symptoms. The edema of IgA nephropathy is mostly edema of the hands and feet and swelling around the eyes. When kidney failure occurs in a patient with IgA nephropathy, shortness of breath may also occur.
Some patients with iga nephropathy have the symptoms of iga nephropathy while their renal function is declining. At this time, the blood pressure of iga nephropathy patients is higher than that of patients with iga nephropathy. The appearance of hypertension symptoms is not a good thing for patients with IgA nephropathy. Hypertension may accelerate the rate of deterioration of renal function in patients with IgA nephropathy, quickly pushing the disease to the stage of uremia. Therefore, patients with IgA nephropathy need to have good control over blood pressure while controlling the condition of kidney disease so as to ensure that the kidney is in a relatively stable environment.
The most common manifestation of IgA nephropathy symptoms is mild proteinuria, urinary protein quantification is generally <1g/24h, a few number of patients may have large amounts of proteinuria or even nephrotic syndrome.
IgA nephropathy patients suffer from kidney function damage, the body can not produce sufficient hormones to produce red blood cells, resulting in anemia. Patients with anemia who have IgA nephropathy often feel cold and tired.
Fifth, physical discomfort
Because of the progressive decline in renal function in patients with iga nephropathy, a large amount of toxins and metabolic waste produced by the body continue to accumulate in the body, and the patient may feel uncomfortable at first, such as nausea, vomiting, nocturnal sleep, no appetite, and itching. A series of symptoms such as fatigue and performance.
Six, paroxysmal hematuria
More common in children. Its gross hematuria occurs after upper respiratory tract infections (tonsillitis, etc.), and some of them also occur after acute gastroenteritis or urinary tract infection. The interval is usually between 24 and 72 hours. Gross hematuria can last for several hours to several days, and then it is converted into persistent microscopic hematuria. Some patients may lose hematuria, but they often have seizures, hematuria, and mild systemic symptoms such as muscle soreness and dysuria. Lumbar pain, or transient blood pressure and elevated urea nitrogen.