Primary iga nephropathy (inflammation) is immune pathological diagnosis name, it is to break out repeatedly to the naked eye hematuria or microscopic haematuria, with different level of proteinuria, renal tissue is given priority to with iga immune globulin sedimentary features. Most of the patients have no abnormal signs, and some patients may have a double renal area to tap pain, edema, and mild, moderate blood pressure.
Level 1, IGA nephropathy Ⅰ: this period of patients with the most normal glomerulus, occasional mild mesangial broadening (section) with and/or are not associated with cell proliferation, renal tubule and renal interstitial does not change, this is the lightest of Lee grading type.
Level 2, IGA nephropathy Ⅱ: this period of patients with glomerular mesangial matrix and focal sclerosis (< 50%), a rare small crescent, renal tubule and renal interstitial without damage.
Level 3, IGA nephropathy Ⅲ: at this time in patients with glomerular shows diffuse mesangial proliferation and broadening (occasionally focal segmental), I see the small new month; The renal tubule and renal interstitial change are out focal renal interstitial edema, occasional cell infiltration, rare renal tubular atrophy, nearby installment symptoms of IGA nephropathy?
Level 4, IGA nephropathy Ⅳ: glomerular lesions in severe diffuse mesangial proliferation and hardening, some or all of the glomerular sclerosis, visible crescent (< 45%). The renal tubules atrophy, the renal interstitial infiltrates, and occasionally the mesenchymal foam cells.
Level 5, IGA nephropathy Ⅴ: glomerular lesions of similar nature Ⅳ level, but more severe, glomerular crescents formation of > 45%; Renal tubule and renal interstitial lesions similar to Ⅳ level, but more serious. The pathological changes of this period of IgA nephropathy is the most serious in IgA nephropathy, so treatment is the most difficult, IgA nephropathy treatment measures and Ⅳ level, just need more rigorous treatment, perhaps on the treatment of time will be relatively long.