Tong shanTang kidney disease blog

www.kidneytcm@yahoo.com

Tongshantang Blog :

Tongshantang hospital blog provides kidney failure,ckd and all kinds of kidney problem as well as diet and nursing knowledge You can reach me at kidneytcm@yahoo.com

Nephropathy associated with hyperuricemia: how to treat?

admin TAGS: 2017-10-11 14:56

Hyperuricemia (HUA), urate deposition in the kidney can lead to chronic urate nephropathy, acute uric acid nephropathy and uric acid nephrolithiasis; on the other hand, kidney disease can influence the excretion of uric acid, the occurrence of secondary HUA. HUA has been shown to be an independent risk factor for chronic kidney disease. Recently, our country issued the first HUA multidisciplinary expert consensus - "multidisciplinary expert consensus on the diagnosis and treatment of  related diseases of hyperuricemia in China".

The timing of treatment and target target value were similar to that of chronic urate. Nephrosis. HUA treatment options for chronic kidney disease are based on primary disease, complications, and renal function. NSAIDs should not be used in patients with chronic kidney disease (G4 to 5) with acute exacerbation of gout. Oral corticosteroids may be given orally or injected with intra-articular injection, and low-dose colchicine can be used according to eGFR.

Lowering uric acid in patients with chronic kidney disease can reduce glomerular uric acid burden and delay progression of chronic kidney disease, and according to the principle of inpidualized treatment, the drugs for inhibiting uric acid production and / or urate removing drugs are selected. Impaired renal function may increase allopurinol toxicity, treatment needs from low starting dose and careful titration. The use of Non GM in patients with mild to moderate renal dysfunction (G1 to 3) and patients with mild to moderate liver injury (Child-Pugh grade A/B) were not required to adjust doses, and G4 to 5 patients were treated with caution. Febuxostat hypersensitivity syndrome and lower incidence of allopurinol; uricosuric drugs benzene bromine Malone can be mild to moderate renal insufficiency (for eGFR 20 to 60 ml/min/1.73 patients, 50 mg/d m2) recommended, uric acid nephrolithiasis and severe renal insufficiency (eGFR<20 ml/min/1.73 m2) disabled patients. To prevent the onset of gout in patients with chronic kidney disease treated with uric acid lowering treatment, prophylactic colchicine should be used at the same time. EGFR<10, ml/min/1.73, M2, or dialysis patients are disabled and may be considered for short-term use of small doses of glucocorticoids.

Nephropathy associated with hyperuricemia: how to treat?
Nephropathy associated with hyperuricemia: how to treat?

 

 

Latest related articles:


  • What are the symptoms of urinary tract infection?

    What are the symptoms of urinary tract infection?

    What are the symptoms of urinary tract infection? Generally sick women, because womens urethra is relatively short, particularly susceptible to infection. Therefore, women must pay attention to daily cleaning, timely detection, early detect...

  • Can diabetic nephropathy be cured?

    Can diabetic nephropathy be cured?

    Diabetes is a very common phenomenon that have great affects to many people, the incidence of diabetes is mainly the elderly, then diabetic nephropathy can be cured ? The following experts together to find out about it! Can diabetic nephrop...

  • Ali is treating Chinese medicine in China

    Ali is treating Chinese medicine in China

    Ali from abroad, after a dozen or so days of detoxification therapy, the condition has been significantly improved. This afternoon, he arranged a medicated bath treatment, just after minutes he was sweating, began to sweat means the body of...

  • Tongshantang: How to recuperating kidney?

    Tongshantang: How to recuperating kidney?

    1, more water Kidney is the cleaners of the human body, and when the kidneys are metabolized to the body waste, these activities require sufficient water to assist. The best time to drink water is: after getting up in the morning, around 10...

  • Diet treatment for chronic kidney disease

    Diet treatment for chronic kidney disease

    Chronic kidney disease is a tough disease, the pathogenesis is complex, and the diagnosis is difficult. How can we treat it? Now lets have the experts explain the diet treatment of chronic kidney disease for us! Chronic kidney disease (CKD)...


Online consultation