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Serum creatinine

Serum creatinine Serum creatinine each hospital is not the same as the measure of normal, serum creatinine in general normal standard is: 44-133 umol/L, when serum creatinine greater than 133 umol/L means that the kidney damage, have renal...

Serum creatinine

May 18, 2017 by Kidney Disease Expert

Serum creatinine

Serum creatinine each hospital is not the same as the measure of normal, serum creatinine in general normal standard is: 44-133 umol/L, when serum creatinine greater than 133 umol/L means that the kidney damage, have renal insufficiency, renal failure. (133umol/L is a period of inflammatory lesion, 186umol/L for renal impairment, 451umol/L for renal failure, and the blood creatinine value of more than 707umol/L indicates advanced (uremia).

Blood creatinine (SCr) normal value:

Male 54 ~ 106 micromo/liter (0.6 ~ 1.2 mg/dl); Female 44 ~ 97 micromo/liter (0.5 ~ 1.1 mg/dl). Children: 24.9 ~ 69.7 umol/L.

Exorbitant cause

The concentration of serum creatinine was determined by the filtration capacity of glomerulus (glomerular filtration rate). When the filter ability declined, the concentration of creatine was elevated. Blood creatinine is much higher than normal, which means the kidney is damaged, and blood creatinine can be more accurate in the case of the renal parenchyma, which is not a sensitive indicator. As the glomerular filtration rate dropped to a third of the normal population, the blood creatinine increased significantly. It means that, because human kidney metabolism ability is strong, the average person when kidney damage is lighter unwell feeling is not obvious, so a lot of people when really have nausea, vomiting, dizziness, actually has been badly damaged kidneys, serum creatinine also began to rise significantly.

Undercurrent cause

Is required when high serum creatinine in patients with kidney problems, kidney metabolic waste, a decrease in the ability of some harmful toxins in the body can't normal eduction body outside, so, as opposed to what was the reason for the low serum creatinine? Due to kidney is the cause of low serum creatinine after the invasion by various causes, the first damaged the phenotypic changes of renal inherent cells, formation of pathological changes, stimulate renal fibroblasts into muscle in fibroblasts, and at the same time the infringement and inspired inherent in normal renal tissue, in the same pathological changes, thus formed the kidney, from part to whole, enlarge the spread process of JiFaShi, thus entered the organ damage period (i.e., kidney damage), at this time due to kidney damage, the discharge of waste function decreases, it caused the accumulation of the creatinine and other toxins in the body to appear in the blood creatinine and urea nitrogen increased, urine creatinine decreased, double kidney filtration rate drop, etc. The patient also has high blood pressure and a high level of swelling and other physical symptoms.

Renal function

Blood creatinine is the most commonly used indicator of kidney function. Blood creatinine is in the normal range, think oneself of kidney function is completely no problem, actually have this kind of thought is wrong.

The blood creatinine value does not reflect the kidney function in time and in time. When most of human kidney pathological damage, glomerular filtration rate decline rate is large (over 50%), serum creatinine increased at this time the situation can be clinically apparent.

As a result, the myth that "blood creatine is normal and the kidney is ok" should be corrected. If normal vegetarian or smaller muscle volume is small, blood creatinine can be low, need to strengthen nutrition.

Clinical presentation

Creatinine is a product of muscle metabolism in the body, and every 20g of muscle metabolism produces 1 mg of creatinine. Creatinine is mainly filtered through the glomeruli and released into the body. In the blood, the creatinine is both exogenous and endogenous, and exogenous creatinine is the final product of the meat-food in the body. Endogenous creatinine is the product of muscle tissue metabolism in the body. When meat intake is flat. The muscle metabolism of the body does not change too much, the formation of creatinine is more constant.

In the early stage of renal failure (compensatory period), the creatinine removal rate decreased and the blood creatinine was normal. When more than 50% of glomerular filtration rate down to normal, serum creatinine began to rise rapidly, so when the serum creatinine is significantly higher than normal, often has serious damage to kidney function. Because of creatinine clearance was affected by glomerular function of enrichment, in the case of impaired renal enrichment, serum creatinine is the most reliable parameter reflecting the glomeruli. Normal male blood creatinine is 53-106gmol/L, and women 44. 2 ~ 97. 2 gmol/L.

Diet specification

Creatinine is a nitrogenous waste product produced by muscle activity. In patients with chronic kidney disease, the levels of creatinine can increase over time. This increase is a red warning sign and kidney function drops. As these levels rise, the levels of nutrients such as potassium and phosphorus often become abnormal.


Patients with higher creatinine levels tend to increase their potassium levels because their kidneys become less able to remove potassium from the blood. The intake limit for adult potassium is less than 2,000 to 3,000 milligrams. NKF defines high-potassium foods, such as over 200 milligrams of potassium. These include potatoes, winter squash, broccoli and beans. The better choice is green pepper, white rice, pasta, mushrooms, Onions, apples and pineapple.


Patients with phosphorus creatinine are often a problem. A nephrologist would recommend a low-phosphorus diet. High phosphorus foods to avoid dairy, lentils, dried beans, chocolate and beer. The limits of macaroni and cheese and toasted pasta, because of the contents of the cheese. Use non-dairy milk instead of milk.


As creatinine levels increase and kidney failure approaches, your kidneys may not be able to produce urine. If that happens, you have to limit how much liquid you consume. Like jelly food, watermelon, frozen desserts are liquid. Get rid of the orange juice and avoid milk. If your phosphorus level is high, you can quench your thirst with a small cup of ice water.


Hypercreatine patients almost always have high blood pressure and usually end up with four or five different blood pressure drugs. It's easier to control your blood pressure, if you follow a low-salt diet. Avoiding processed meat and canned soup is a good start. Just be careful to avoid mung bean dishes, often accompanied by such dishes, if your potassium and phosphorus are high.


Patients with high creatinine levels tend to change the amount of protein they consume. Many patients have low protein diets to slow the progression of kidney disease and minimize the risk of nitrogen waste in the blood. Other patients start dialysis after a high-protein diet to prevent muscle atrophy and replace amino acids with the blood dialysis of the patient. Ask your doctor if you need to change your protein intake.


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