Maternal high risk maternal urinary protein found positive urine protein is considered due to pregnancy induced hypertension syndrome caused by (in the past called toxemia of pregnancy), the disease can cause renal damage should actively adjust blood pressure, avoid drugs impair kidney function, and rest in bed for most in protein can disappear after delivery.
Massive proteinuria is one of the main risk factors to promote the progression of chronic kidney disease to end stage renal failure, so it should be an important target for the treatment of chronic kidney disease. Mesangial toxicity of urinary proteins: In the model of proteinuria and nephropathy, apolipoprotein B with low density lipoprotein (LDL) and very low density lipoprotein (VLDL) and apolipoprotein A deposition in the glomerulus may also ultimately causes glomerulosclerosis.
Urine protein toxicity to proximal tubule cells: When proteinuria occurs, the amount of protein entering into the renal tubular epithelial cells increases, and the lysosome activity increases, suggesting that the protein causes lysosomes to overflow into the cytoplasm of the tubules, and subsequent cell injury can stimulate inflammation and scar formation.
In general, there are two reasons for high urinary protein in pregnant women, one is high pregnancy, the second is nephritis, the former generally do not have to worry too much, pay more attention to the latter, the latter is more harmful, this time need consult doctor how to treat it.
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