How to treat chronic renal failure with urinary tract infection? In normal life, chronic kidney disease has been difficult to treat, not only complex and long course of disease, chronic renal failure is one of the typical example. When the disease is associated with urinary tract infection, the patient's suffering is extremely serious. Then, how should we treat the chronic kidney failure patients with the characteristics of this disease?
First of all, it is necessary to understand that when the concurrent infection, chronic renal failure is extremely difficult to cure, the main reason is the chronic renal failure when the kidneys have shrunk, poor blood flow, the drug is not easy to achieve effective concentration, And urine to obtain effective antibacterial concentration and not cause accumulation of poisoning more difficult; antimicrobial agents in the kidney of the effective concentration to be very slowly to achieve, so the bacteria prone to drug resistance; infection is usually obtained in the hospital, the pathogens are mostly resistant Drug strains; bilateral renal dysfunction is not equal, antibacterial drugs on both sides of the kidney concentration is different in the side of the poor side of the antibacterial drug concentration is low, can not play a role.
It can be seen from the above, the incidence of chronic renal failure is difficult to cure, but patients should not lose confidence. Because the kidney is the main way of excretion of many antibiotics, chronic renal failure caused by delayed excretion of drugs, accumulation, increased renal toxicity, therefore, when the safe and effective use of antibiotics in patients with chronic renal failure complicated with urinary tract infection, should be based on the drug sensitivity of antibiotics, the main metabolic process, and excretion pathway of the kidney toxicity, combined with the patient's creatinine the clearance rate, and whether the patient for dialysis treatment, comprehensive analysis, to determine the type of antibiotic administration route, method and dose.