Adult polycystic kidney disease is an autosomal dominant genetic disease, almost all bilateral, although the literature has been reported in infants suffering from adult polycystic kidney disease in infants, but unlike adults, infantile polycystic kidney disease is an autosomal recessive genetic disease, prognosis and short survival time, usually 40 of adult polycystic kidney the age does not appear symptoms of polycystic kidney volume than normal renal cyst, the surface with different sizes, so the adult polycystic kidney disease genetic?
Adult polycystic kidney disease is a familial dominant hereditary disease, which is called autosomal dominant polycystic kidney disease.
Polycystic kidney cyst can be "born" with time, when the cyst grows to a certain stage, the small channel connected to the capsule and the kidney is blocked by the proliferation of tissue, the cyst fluid can not be ruled out gradually increased. The cyst oppresses the renal tissue, leading to the atrophy of the tubules, the disappearance of the small ball and the damage of the renal function. A kidney size, from the size of soybean to egg size, when the abnormal growth of the cyst and squeezed surrounding renal tissue, the normal kidney tissue caused by loss of function, renal insufficiency, chronic renal failure, even uremia.
Cysts are not only a violation of the kidney, but also the invasion of the liver and pancreas, so patients with polycystic kidney disease are often found to have polycystic liver disease. Treatment using puncture decompression therapy, but can not cure polycystic kidney. Because there is no effective treatment, so rely on good control of blood pressure, disable nephrotoxic drugs, protect renal function, blood stasis is helpful to delay the progression.
Clinical manifestations of adult polycystic kidney disease
Adult polycystic kidney disease is generally born with cysts, but smaller, not easy to find, 20 years old before it is generally difficult to find, but the family if there are cases of polycystic kidney disease, should be early detection, regular follow-up. 30-40 years old, showed renal cyst growth faster, with vesicles of different sizes, ranging in diameter from a few millimeters to several centimeters, sac urine liquid.
Often occur in patients with different clinical manifestations: persistent or paroxysmal abdominal pain, fatigue after the increase; intermittent gross hematuria; abdomen touch the size of the masses; hypertensive patients with headache and dizziness; frequent micturition symptoms such as urinary tract infection; poor appetite, nausea, vomiting and other renal insufficiency. Urinary tract X-ray, B ultrasound, CT, nuclear magnetic resonance and other tests can help to diagnose.
In short, if suffering from this disease, we should go to a regular hospital for treatment, the disease control in a certain range, do not let the disease develop rapidly, if the development to a certain program will turn to more severe disease, more difficult to treat.