According to the data, the incidence of chronic kidney disease in China is 10.8%, and the country is estimated to have 150 million patients with chronic kidney disease. Among them, IgA nephropathy is the most common type of chronic nephritis.
Nephrologists have analyzed more than 10 thousand cases of renal biopsy. The proportion of patients with IgA nephropathy is 45%. The number of patients with glomerulonephritis is not large. Part of the uncontrolled high blood pressure, urinary protein in patients with disease onset of a few years or 10 years after the threat of uremia.
What are the characteristics of IgA nephropathy? Hematuria occurs shortly after a cold, with gross hematuria, which recurs frequently within a few years, or with persistent asymptomatic hematuria under microscope.Hematuria is a prominent feature of IgA nephropathy, some patients with hematuria also associated with proteinuria.
An authoritative journal of kidney disease - JASN published a prognostic analysis of IgA nephropathy. If urinary protein is less than 1 g / day, kidney survival rate is high, that is to say the probability of uremia is low. This part of patients do not have to worry too much, adhere to scientific treatment, are generally far from uremia. However, in patients with urinary protein greater than 3 g / day, renal function declined more than 20-fold faster than proteinuria of less than 1 g / day. Fifteen years later, nearly 80% of patients progressed to uremia.
In patients with iga nephropathy whose serum creatinine was greater than 148 umol / l, the incidence of end-stage renal failure was more than 20 times higher than that of patients with serum creatinine lower than 111 umolol / l. Also highlighted: hypertension is an important factor in the transition from nephropathy to uremia. Blood pressure over 130 / 80 mmhg indicates that the disease is moving towards uremia.
ICan iga nephropathy be cured? Iga nephropathy is unreasonable, terrible because there is no way to prevent it. China now has 150 million patients with chronic kidney disease. IgA nephropathy which is not a minority, about 40 million. These 40 million people, or because of human genetic defects, or because of acquired respiratory tract, digestive tract, urinary tract infections, colds, suffering from IgA nephropathy is an unavoidable event.
Only 90 to 95 percent of the young patients didn't know they were sick because not every patient was warned of hematuria with gross hematuria. Many IgA nephropathy in the event of unknowingly, has been moving in the direction of uremia until the final fall requires lifelong dialysis only to find themselves sick.