The clinical manifestations of chronic glomerulonephritis are various symptoms of chronic glomerulonephritis is not obvious, it can increase the urine protein showed only urine red blood cells, visible tube type. The symptoms of chronic glomerulonephritis is sometimes fatigue, tiredness, loss of appetite, backache, edema and sometimes without, for eyelid edema and (or) lower extremity pitting edema, no effusion. Glomerular filtration function and renal tubule concentration dilution function were normal or mild impairment. Some patients may be more prominent performance for persistent moderate hypertension, can appear retinal hemorrhage, exudation, and edema of optic disc.
Some patients can be manifested as a large number of proteinuria (urine protein 3.5g/24h), and even showed nephrotic syndrome. In the nonspecific viral and bacterial infections after the disease can appear acute exacerbations in patients with chronic nephritis, acute attack, can be a massive proteinuria, even hematuria, tube type increased, edema, hypertension and renal function. After proper treatment of the disease can be restored to the original level, but some patients lead to disease progression, into the uremia stage. Because of chronic nephritis can be different in nature, the disease process has significant difference. From the first discovery of abnormal urine to the development of chronic renal failure, can last for years, even decades. High blood pressure, infection, improper diet, the use of nephrotoxic drugs and continuous proteinuria, can accelerate the chronic nephritis into chronic renal failure. There are 3 types of symptoms of chronic glomerulonephritis:
1 the common type of chronic glomerulonephritis is the most common type of chronic glomerulonephritis. Patients can have weakness, tiredness, waist pain, loss of appetite. Sometimes no edema, usually not very serious. Mild to moderate hypertension. The face was pale yellow, pale, the fundus artery was thin, and there was the phenomenon of arteriovenous cross compression. Urine visible moderate proteinuria (less than 3.0g/d), urine red blood cells and a variety of tube. Creatinine clearance decreased; phenol discharge to reduce urinary concentrating function and serum creatinine and blood urea nitrogen increased, azotemia appears. Have anemia, different levels of ESR and serum albumin was slightly lower, slightly higher cholesterol. Slow progression of this type of disease, due to renal failure.
2 chronic nephritis nephropathy is a prominent manifestation of chronic glomerulonephritis. The presence of massive proteinuria (no selective proteinuria). Urinary protein excretion per day exceeds 3.5g/dl. A high degree of edema and decreased plasma albumin, usually below 3g/dl, hypercholesterolemia, over 250mg/dl. Examination of urinary sediment, can have red blood cells and various tube type. A normal or moderate increase in blood pressure. Normal renal function or damage, blood creatinine and blood urea nitrogen increased, creatinine clearance and excretion were lower. Patients may have anemia, erythrocyte sedimentation rate accelerated obviously. The nephritis can be relieved by proper treatment.
3 in addition to the common manifestations of chronic glomerulonephritis, the symptoms of chronic glomerulonephritis, hypertension, hypertension, and the general antihypertensive drugs are not very sensitive. Often cause serious retinal hemorrhage or even exudate, optic disc edema, decreased visual acuity. With kidney injury, urine have different levels of urine protein and urine abnormality, this type of rapid deterioration of renal function, prognosis.
The above symptoms of chronic glomerulonephritis are not absolute, and there is a cross between each type. Some patients have the same type of kidney disease and hypertension, can be mixed. However, understanding the symptoms of chronic glomerulonephritis is of special significance in the prevention and treatment of chronic glomerulonephritis.