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What are the stages and criteria of chronic renal failure?

Chronic renal failure (CRF) is a kind of clinical syndrome caused by a variety of symptoms and metabolic disorder caused by the progressive deterioration of renal function. So what are the stages and criteria of chronic renal failure? Lets...

What are the stages and criteria of chronic renal failure?

Mar 16, 2017 by Kidney Disease Expert

Chronic renal failure (CRF) is a kind of clinical syndrome caused by a variety of symptoms and metabolic disorder caused by the progressive deterioration of renal function. So what are the stages and criteria of chronic renal failure? Let's get together.

1 renal function compensatory phase: this period of renal units reduced by about 20%-25%, glomerular filtration rate reduced to 30-60 ml / min. Renal reserve capacity has been lost, but for the excretion of metabolites, regulation of water electrolyte and acid-base balance ability is good. Therefore, there is no special clinical manifestations, blood enzymes and blood urea nitrogen is usually normal or slightly elevated.

2 of the stage: the nephron was reduced by 50%-70% and the glomerular filtration rate was reduced to 1 ml / min. Dysfunction of renal concentration, nocturia or polyuria, varying degrees of anemia, and often the presence of nitrogen, blood creatinine, urea nitrogen increased. Clinical weakness, anorexia, nausea and mild discomfort.

The 3 stage of renal failure: nephron reduction of about 70%-90%, the renal function is severely impaired, glomerular filtration rate decreased to 0-5 ml per minute, kidney cannot maintain the body's metabolism of water and electrolyte and acid-base balance and homeostasis. Serum creatinine and urea nitrogen were significantly increased, urine concentration and dilution dysfunction, and acidosis, retention of water and sodium, low calcium, high phosphorus, high potassium and other disorders.

4 uremia stage: the renal unit was reduced by more than 90%, the glomerular filtration rate dropped to less than 0-5 ml per minute, the clinical symptoms of the renal failure were more obvious, which showed that the systemic multiple organ failure. This need to rely on dialysis to sustain life. Often due to hyperkalemia, cerebral edema, pulmonary edema, heart failure and sudden death.

Chronic renal failure is a serious disease, need to do early detection, early treatment, active treatment of the original disease, adjuvant treatment of other diseases.

 

 

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