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Why does blood pressure rise in patients with acute glomerulonephritis?

About 80% of the acute glomerulonephritis patient can occur hypertension, is generally mild and moderate hypertension, adults often at 130 ~ 160 / 90 ~ 100mmhg, blood pressure fluctuations, is a rare, serious hypertension, and may be associ...

Why does blood pressure rise in patients with acute glomerulonephritis?

Oct 01, 2017 by Kidney Disease Expert

About 80% of the acute glomerulonephritis patient can occur hypertension, is generally mild and moderate hypertension, adults often at 130 ~ 160 / 90 ~ 100mmhg, blood pressure fluctuations, is a rare, serious hypertension, and may be associated with retinal artery hemorrhage, exudation, papilledema or hypertensive encephalopathy.

Why does blood pressure rise in patients with acute glomerulonephritis?

The causes of acute glomerulonephritis patients with hypertension are:

Retention of water and sodium: due to various factors leading to retention of sodium and water, increased blood volume, resulting in capacity dependent hypertension.

Increased renin secretion: renin is a special proteolytic enzyme that transforms inactive angiotensin elements in plasma globulin into active angiotensin, a potent vasoconstrictor. Due to renal parenchymal ischemia, stimulation of renin angiotensin secretion increases, thereby contributing to arteriolar contraction, increased peripheral resistance, and renin dependent hypertension.

The decrease of renal depressor substance after renal parenchymal damage is one of the causes of hypertension. Most of the hypertension caused by glomerulopathy are volume dependent, and few are renin dependent. Type two hypertension, however, is often mixed and sometimes difficult to separate.

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