Glomerulonephritis, also known as nephritic syndrome, is a common kidney disease. It is a disease characterized by a group of syndromes occurring in bilateral kidneys and glomeruli due to various causes.
The main clinical manifestations of glomerulonephritis are proteinuria, hematuria, edema and hypertension. Because of the insidious renal disease, the early symptoms of glomerulonephritis are not obvious and are easily overlooked. Clinical investigation showed that patients with glomerulonephritis often lose the best timing of treatment, resulting in progressive renal fibrosis, eventually developed into renal failure, uremia, using conventional dialysis or kidney transplant to maintain life.
Glomerulonephritis can be pided into primary glomerulonephritis and secondary glomerulonephritis. Secondary glomerulonephritis is caused by other diseases (such as diabetes, hypertension, systemic lupus erythematosus, allergic purpura, vasculitis, etc.) and is involved in the systemic disease of the kidney. Primary glomerulonephritis is considered secondary to glomerulonephritis after primary glomerulonephritis. It can be pided into: acute, chronic and acute nephritis syndrome, occult nephritis (asymptomatic hematuria and / or proteinuria). Commonly referred to as glomerulonephritis, if not explained, often refers to primary chronic nephritis. According to the renal biopsy, the pathology of chronic glomerulonephritis can be pided into mesangial proliferative glomerulonephritis, focal segmental glomerulosclerosis, membranous nephropathy, mesangial capillary glomerulonephritis, and sclerosing nephritis. The pathological changes of acute nephritis characterized by glomerular crescent formation, also known as crescentic glomerulonephritis. In addition to the majority of acute poststreptococcal glomerulonephritis after treatment can restore and relieve, other acute nephritis syndrome presenting as glomerulonephritis may have differences in treatment, therefore, the renal biopsy should be carried out in time for the diagnosis of glomerulonephritis which is not typical of acute nephritis.