The occurrence of polycystic kidney and renal failure is the process of gradual fibrosis of functional renal units. During this process, the renal functional cells are a progressive damage process. Therefore, the treatment of polycystic kidney and renal failure should be based on the protection of renal functional cells.
Renal fibrosis is a pathophysiological change that is a progressive process in which the kidney functions from health to injury, to destruction, and to loss of function. Kidney due to trauma, infection, inflammation, blood circulation, stimulate the immune response and other risk factors, its inherent influence, the formation of cicatricial kidney, until the complete loss of organ function. The process of fibrosis and hardening of the natural cells in the kidney is the process of renal fibrosis.
For example, patients with polycystic kidney disease should be treated primarily to restore the function of these renal units. Therefore, patients with polycystic kidney disease must understand the classification of renal fibrosis and repair the damaged renal function units during the reversible phase of renal fibrosis.
The formation of renal fibrosis can be pided into:
One, reversible stages of fibrosis formation and progression;
Two, uremia formation stage.
In the reversible stage of renal fibrosis, although the structure and function of the kidney has changed, the damaged cells can still exercise part of the original function, can be treated through the damaged cells reversed to normal cells, restore the original function. But uremia period, although can block the process of renal fibrosis, but it has become uremia kidney tissue, it is difficult to repair. Therefore, the reversible stage of renal fibrosis is a key link to block renal fibrosis, and is of great significance for the rehabilitation of renal disease and the reversal of renal failure. It is the best treatment period for patients with high attention. Experts said that if the polycystic kidney failure in polycystic kidney failure can be repaired so the process will be curbed in renal cell damage, it will significantly reduce the end-stage renal failure, the occurrence of uremia.
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