There are many reasons that cause the renal failure，both the external causes and the internal causes. If the renal failure cannot be treated effectively in time，it will cause the conditions more and more serious，irrespective of age. The research shows that a quarter of renal failure patients have closer genetic connection . That means the renal failure have certain heredity. What’s more,22.8% of the renal failure patients have the symptoms of the disease in the research. That verified the renal failure has the possibility of the character. So remind those people who have a family history of the disease that they had better go to hospital for regular routine urianlysis，so that the renal failure which may happen can be discover earlier.
It is generally acknowledged that the main causes of the renal failure are related to spleen and kidney deficiency loss and the inducements are the exogenous pathogen and defatigation. The first cause：exogenous pathogenic factors，since most of patients develop from geomancy，parts of patients don’t have a history of geomancy，but they have a history of repeated infection of wind-heat and damp-heat. The second cause：internal loss，due to many reasons causing weakening zhengqi，decreasing resistance、 unbalance of yin and yang and external wind-heat and damp-heat such as other chronic disease、inherent insufficiency、acquired malnutrition、the attack of the six external factors、seven emotions hurts、excessive overstrain、drugs lesion、intemperance in sexual life and deficiency of kidney or natural decline of kidney function when getting old.
There are three kinds of factors resulting in the renal failure：The immune response of toxic substances to drugs and the infection or disease such as acute glomerulonephritis can all cause great damage to kidney，which is enough to cause the renal failure;The sudden decline of blood pressure、severe bleeding(such as trauma which suffers being squeezed)、or heart attack can all cause psychiatric disorders，which will damage the kidney eventually. The last factors is that blocking happens in somewhere of the urinary tract，which cause the sudden and entire blocking of uroflow.