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Why chronic renal failure complicated with urinary tract infection ?

Chronic pyelonephritis can cause chronic renal failure. On the contrary, urinary tract infection is also easy to occur on the basis of chronic renal failure caused by various chronic kidney diseases. The incidence of chronic renal failure c...

Why chronic renal failure complicated with urinary tract infection ?

Nov 08, 2017 by Kidney Disease Expert

Chronic pyelonephritis can cause chronic renal failure. On the contrary, urinary tract infection is also easy to occur on the basis of chronic renal failure caused by various chronic kidney diseases. The incidence of chronic renal failure complicated by urinary tract infection is not the same, ranging from 14% to 74%. The incidence of urinary tract infection caused by obstructive nephropathy is the highest, up to 71%. Common diseases such as polycystic kidney, gouty kidney and renal tubular acidosis are also complicated with urinary tract infection.

Why chronic renal failure complicated with urinary tract infection ?

The mechanism has the following: ①all kinds of chronic kidney disease caused by renal scarring, renal obstruction caused local bradyuria; ②the decline of renal function, urine flow decreased, urine is stored in the bladder is prolonged, is conducive to the breeding of bacteria; ③disease of human immunity and resistance to decline in chronic renal failure when the leukocyte migration and phagocytosis decreased, and uremia patients with anorexia, malnutrition, anemia, metabolic acidosis and will further weaken the resistance and susceptible to urinary tract infection.

Chronic renal failure complicated with upper urinary tract infection can cause congestion and edema of renal interstitium, aggravate renal function damage, and cause acute renal failure in severe cases. If the infection can be controlled or cured, it can improve the renal function, improve the condition, even relieve uremia, otherwise the renal function will deteriorate rapidly and even cause death.

The adverse consequences of chronic renal failure complicated with urinary tract infection: the deterioration can lead to chronic renal insufficiency; the low activity of pyelonephritis, can cause severe sepsis sepsis; chronic renal failure, approximately 20% by urinary tract infection and. (3) the kidneys of long-term dialysis patients can develop cysts. Cysts can be changed into renal abscesses if they are infected.

 

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