Adult patients with chronic renal failure (crf) have a high risk of developing complications from heart disease. it is thought that the treatment with statins reduces cholesterol and reduce the risk of death and complications from heart disease.
we examined 50 studies published before june 2012 on treatment with statins in more than 45 000 people with ckd who were not in need of a dialysis treatment. we found that statins reduced the risk of death and major cardiac events (20%). treatment with statins is also shown to be effective in reducing disease and death in patients with ckd, heart and heart disease. in these patients, treatment with statins reduces the risk of heart attack by 50%.
statins have potential adverse effects on liver and muscle as well as certain types of cancer. we found that these questions were not well documented in the studies we reviewed, and these effects are not well understood.
although the use of statins did not reduce the risk of progression of clear renal failure, it can be recommended to reduce the risk of death and cardiac events in people who are in the early stages of renal insufficiency. however, the potential side effects are unclear and need to be further studied.